Meet VarSee Lung.

VarSee Lung measures blood biomarkers and reads their combined pattern with specialist machine learning. It is our first disease-specific product.

Available for research use onlyAsk about availability
BioMarkIQ VarSee — the leaf mark

VarSee Lung.
Explained in three minutes.

Why lung cancer is so often found late, and how VarSee Lung reads a panel of blood proteins with machine learning.

Video · 2 min 52 s · with sound · plays in Google Drive’s player. VarSee Lung is available for research use only and is not for diagnostic use.

Most lung cancer in India
is found late.

Lung cancer is the most common cancer among men in India and, in the latest IARC estimates (opens in a new tab), the leading cause of cancer death. Most people learn they have it at an advanced stage, often after months of treatment for something else. Found earlier, many more people are alive five years on.

THE SURVIVAL GAP

Stage at diagnosis changes the odds.

Localised: 65.5% were alive five years after diagnosis. Found while the cancer is still confined to the lung. 24% of US lung cancers are found at this stage.

Five-year relative survival, lung and bronchus cancerUS SEER, 2016–2022 · published data, not VarSee results
Read the data as a table
Five-year relative survival by stage at diagnosis, US SEER 2016–2022
Stage at diagnosisFive-year relative survivalShare of US cases diagnosed
Localised65.5%24%
Regional38.2%21%
Distant10.5%51%

Early enough
to operate.

Non-small-cell lung cancer, the most common type, can often be removed with surgery when it is found at stage I or II; guidelines name surgery the treatment of choice. Found later, surgery is rarely an option. Large screening trials show how much changes when cancer is found earlier.

“For stage I–II NSCLC patients and no medical contraindications to surgery, surgical resection remains the treatment of choice.”

SEOM 2018 guideline
Stage at diagnosis, by screening armNational Lung Screening Trial · published data, not VarSee resultsSource 2

Low-dose CT: 50.0% of lung cancers were found at stage I (520 of 1,040) and 21.7% at stage IV, after it had spread.

Read the data as a table
Lung cancers by stage at diagnosis in the National Lung Screening Trial
Screening armCancersStage IStages II–III and otherStage IV
Low-dose CT1,04050.0% (520)28.3%21.7% (226)
Chest X-ray92931.1% (289)32.8%36.1% (335)

Published trial results, not VarSee results

  1. 92.5%

    of stage I cancers in the CT arm were treated with surgery, alone or with other treatment.Source 2

    NLST, 53,454 people at high risk, United States
  2. 20%

    fewer deaths from lung cancer with low-dose CT screening than with chest X-ray.Source 2

    NLST, relative reduction 20.0%
  3. 24%

    fewer deaths from lung cancer among men after ten years than without screening.Source 3

    NELSON, rate ratio 0.76 at ten years, Netherlands and Belgium
IN INDIAN HOSPITAL SERIES

Few patients reach surgery, and most are diagnosed late. That is the gap earlier detection has to close.

  • 3%

    of 1,013 patients with treatment records at AIIMS New Delhi had surgery. 95% of non-small-cell lung cancers were diagnosed at stage III or IV.Source 4

    1,862 patients, 2008–2018
  • 6%

    of patients at Tata Memorial Hospital, Mumbai, had surgery. The largest group (43%) was at stage III on arrival.Source 5

    489 patients, 2008–2009

What is VarSee Lung?

VarSee Lung combines a panel of blood biomarkers with a specialist model for lung-cancer research. The proteins are measured using automated immunoassays.

The model reads the measurements together with clinical context, rather than treating each marker as a separate answer.

A BioMarkIQ team member in a lab coat gives a blood sample.
It starts with one blood draw.

Why measure more
than one biomarker?

A marker can be useful without telling the whole story. Complementary biomarkers offer different views of the same disease.

The illustration shows how a second measurement can separate overlapping patterns.

Explore the science
How a signal is judged
FIRST SIGNAL →SECOND SIGNAL →THRESHOLD

Find people with the condition.

Of the people with the condition, how many does the test find? Everyone past the threshold is flagged; squares short of it are missed.

Identify people without it.

Of the people without the condition, how many does the test correctly clear? Circles past the threshold become false alarms.

Add a second signal.

A second measurement can pull the groups apart, so fewer are missed and fewer are flagged by mistake. Whether a real panel does this is what validation has to show.

Build for sensitivity.
Build for specificity.

Finding a cancer signal and avoiding a false alarm are both central to early-detection research. We study these questions together, with attention to disease stage and the population being tested.

That is why we are building from the bottom up: a focused panel, a disease-specific model, and an evaluation designed for the question.

Review the evidence
BEFORE YOU ENQUIRE

Your questions about access.

Can I take VarSee Lung as a routine cancer screening test?

VarSee Lung is currently available for research use only, not for diagnostic use or routine cancer screening. Contact BioMarkIQ to ask about research-use access in your location. Your clinician can advise you about established screening options.

Where can I access VarSee Lung?

Email info@biomarkiq.com with your city, country, and whether you are asking for yourself, a clinic, or a laboratory. The team can discuss current research-use access options and the next steps.

How much does VarSee Lung cost?

Contact BioMarkIQ for current research-use pricing and access arrangements in your location.

Does VarSee Lung test for every cancer?

No. VarSee Lung focuses on lung-cancer research. BioMarkIQ is developing further disease programmes toward multi-cancer early detection; VarSee Lung is not an all-cancer test.

Interested in
VarSee Lung?

Ask about research-use access in your location. Researchers and laboratories can also contact us about study collaborations and pilots.

Ask about the test
01

Research groups

Connect a disease question with biomarker and model development.

02

Laboratories

Discuss measurements, research workflows, and a potential pilot.

03

Commercial partners

Combine your capabilities with our panels and models.

Ethics approval is in place at three Tata Memorial Centre hospitals.

One disease is the beginning.

Our path toward MCED